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High throughput protein-protein interaction data: clues for the architecture of protein complexes

James R Krycer1 email, Chi Nam Ignatius Pang1 email and Marc R Wilkins1,2 email

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia

Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia

author email corresponding author email

Proteome Science 2008, 6:32doi:10.1186/1477-5956-6-32

Published: 26 November 2008

Additional files

Additional file 1:

Compilation of high-throughput data for the 19S RP and 20S CP proteasomal subunits, as well as other proteins in Complexes 2 and 75 in Gavin et al [12]. A table that illustrates the degree to which high throughput complexes reflect the proteins of the proteasome.

Format: PDF Size: 72KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 2:

Compilation of high-throughput data for proteins in the mediator and SAGA complexes and associated proteins described in Complex 81 and 445 in Gavin et al. [12]. A table that illustrates how high throughput complexes reflect the protein subunits of the mediator and SAGA complexes.

Format: PDF Size: 17KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 3:

Classification of proteasomal and coactivator protein subunits from Gavin et al [12]. A table showing core, module and attachment classification of proteins in the proteasomal and coactivator protein complexes.

Format: PDF Size: 12KB Download file

This file can be viewed with: Adobe Acrobat Reader


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