Table 1 |
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Variation of Pooled Sample intensities from Individual Sample intensities, using independent clustering (A) or imposed clustering (B). |
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| Set, Significance level |
Number of peak clusters in pooled samples retained for analysis |
Median number of SDs pooled control cluster intensities are from mean individual sample intensities (IQR) |
Median number of SDs pooled case cluster intensities are from mean individual sample intensities (IQR) |
Median number of SEs pooled sample case to control ratios are from means of individual sample ratios (IQR) |
Proportion of pooled sample case to control intensity ratios that lie less than 0.25 SEs from means of individual sample ratios |
|
|
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| A, all |
97/197 (40.9%) |
0.37 (0.18 – 0.61) |
0.39 (0.16 – 0.62) |
0.20 (0.10 – 0.33) |
59/97 (61%) |
| A, p < 0.05 |
21/35 (60%) |
0.29 (0.12 – 0.37) |
0.33 (0.17 – 0.44) |
0.16 (0.11 – 0.36) |
13/22(62%) |
| A, p < 0.05 (manually added peaks, see text) |
35/35 (100%) |
0.34 (0.16 – 0.56) |
0.33(0.18 – 0.57) |
0.20 (0.12 – 0.45) |
19/35 (54%) |
| B, all |
- |
0.40 (0.20 – 0.67) |
0.43 (0.19 – 0.80) |
0.21 (0.11 – 0.43) |
109/197 (55%) |
| B, p < 0.05 |
- |
0.30 (0.19 – 0.46) |
0.40 (0.19 – 0.58) |
0.14 (0.09 – 0.40) |
23/35 (66%) |
|
SD: standard deviation; SE: standard error; SDs and SEs are absolute in value, ignoring direction. IQR: inter-quartile range | |||||
Sadiq and Agranoff Proteome Science 2008 6:16 doi:10.1186/1477-5956-6-16 |
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