Table 1

Hippocampal proteins whose abundance differs between conditions with protein ID from Swiss Prot database, analysis and identification information.

Master #
Protein ID
Name
Function
Average ratio
p-value
pI
Mw
Mowse score

1169
AINX_RAT
α-internexin
Y
-1.52
0.000082
5.2
56253
108
1166
DPYL2_RAT
Dihydropyrimidinase-related protein 2
D
-1.64
0.012
5.95
62638
100
1192
GDIA_RAT
Rab GDI α
G
-1.31
0.045
5
51074
100
1489
GFAP_RAT
Glial fibrillary acidic protein
Y
-1.35
0.04
5.35
49970
90
1781
KCRB_RAT
Creatine kinase type B
M
-1.26
0.045
5.33
42970
236
971
NSF_MOUSE
Vesicle fusing ATPase
T
-1.33
0.0067
6.52
83083
68
1753
NDUS2_MOUSE
NADH ubiquinone oxidoreductase
M
-1.22
0.012
6.52
52991
69
1230
PDIA3_RAT
Protein disulfide isomerase A3
C
1.83
0.033
5.88
57044
100
1869
PURA_MOUSE
Transcriptional activator protein Pur-α
A
-1.23
0.025
6.07
34976
54
2462
SNAA_RAT
α-soluble NSF attachment protein
T
-1.37
0.017
5.3
33627
107
1131
TPMT_CANFA
Thiopurine S-methyltransferase
C
-1.42
0.0071
6.46
28752
87
532
YPEL4_RAT
Protein yippee-like 4
?
1.53
0.036
8.42
14762
44

In the Function column, A = transcriptional regulation, C = protein translation, folding and degradation, D = development, G = cell signalling, M = cell metabolism and energy, S = stress, chaperone, T = transport and vesicle trafficking, Y = cytoskeleton. In the Average ratio column, a negative number corresponds to a protein more abundant after 4 hours of sleep deprivation than 4 hours of sleep. The average ratio represents the ratio between the average protein abundances in the different conditions (n = 6), as computed by the DeCyder software. Other abbreviations: pI = identified isoelectric point ; Mw = identified molecular weight. Mowse score as defined by Pappin et al. [62]

Poirrier et al. Proteome Science 2008 6:14   doi:10.1186/1477-5956-6-14