|
Differentially expressed proteins in serum from normal glucose tolerant and type 2 diabetes mellitus individuals |
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| Peak (Da) |
Array |
T2DM vs. NGT |
|
|
||
| 5915 |
IMAC30 |
↑ |
| 6095 |
IMAC30 |
↑ |
| 7778 |
IMAC30 |
↑ |
| 8944/8949 |
IMAC30/CM10 |
↑ |
| 9133 |
IMAC30 |
↑ |
| 9303/9305 |
IMAC30/CM10 |
↑ |
| 9443 |
CM10 |
↑ |
| 9505 |
IMAC30 |
↑ |
| 13923 |
CM10 |
↑ |
| 17294 |
IMAC30 |
↓ |
| 28166 |
IMAC30 |
↓ |
| 37887 |
IMAC30 |
↑ |
| 51259 |
IMAC30 |
↓ |
| 66355/66267 |
IMAC30/CM10 |
↓ |
| 79040 |
CM10 |
↓ |
|
Amounts of serum proteins were determined by calculating heights of peaks found in SELDI-TOF mass spectra using the immobilized metal affinity capture (IMAC30) and cationic exchanger (CM10) arrays. Serum samples were obtained from three normal glucose tolerant (NGT) and three type 2 diabetes mellitus (T2DM) subjects. Protein masses, after applying inclusion criteria (signal to noise ratio > 10, percentage of peaks > 20%) on the spectra, are indicated. Significant (p < 0.05, Mann-Whitney U-test) up- (↑) and down (↓) regulations are noted. | ||
Sundsten et al. Proteome Science 2006 4:22 doi:10.1186/1477-5956-4-22 |
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