Figure 2.

Mass spectra of serum fractions showing the 9443 Da biomarker. SELDI-TOF mass spectra of serum after fractionation. Upper trace shows spectrum of the anionic fraction 5. Middle trace shows spectrum of the reverse phase beads fraction with 20 % acetonitrile. Lower trace shows the reverse phase beads fraction with 30 % acetonitrile. The abundant 66 kDa protein (albumin) was reduced in reverse phase fraction with 20 % acetonitrile (hatched area). The arrow indicates the 9443 Da biomarker.