Table 1

Representation of an example TFBS. Two sequence-based representations of the same TFBS, a consensus sequence and a position specific scoring matrix (PSSM). The example used here is the binding site of the early growth response protein 1 (EGR-1, Zif268), which is a zinc finger protein.

CONSENSUS
T
G
C
G
T
G
G
G
C
G

POSITION
1
2
3
4
5
6
7
8
9
10

SCORING MATRIX
A
5
7
0
2
0
31
0
0
13
0

C
3
0
98
0
2
0
0
0
76
0

G
5
93
0
98
14
69
100
100
0
100

T
87
0
2
0
84
0
0
0
11
0

Höglund and Kohlbacher Proteome Science 2004 2:3   doi:10.1186/1477-5956-2-3